Overview The Senior Manager, US Commercial Training & Development – TTR Franchise reports to the Associate Director. This role involves developing and implementing capability building strategies, plans and processes that drive measurable field performance and business outcomes within the TTR franchise. The Training Manager will collaborate cross-functionally in a matrix organization with commercial leadership, field force, marketing, access, headquarters teams, medical, legal, and external vendors. This collaboration will involve facilitating group discussions to determine the training needs and deliverables for US commercial team members. Key Responsibilities Support the design and execution of capability-building strategies that align to TTR Franchise business priorities and drive measurable field performance outcomes Translate business goals into targeted learning strategies and solutions that enhance field effectiveness across the customer journey Partner with Commercial Leadership and cross-functional stakeholders (Marketing, Market Access, Medical, Patient Services, and Operations) to identify performance gaps and define capability needs Act as a trusted advisor, contributing to decisions related to field execution, capability development, and training strategy Design and deliver high-impact learning experiences (live, virtual, and digital) that prioritize application, practice, and behavior change over knowledge transfer Ensure learning solutions are scalable, efficient, and minimize time out of territory while maximizing impact Manage the development and execution of new hire onboarding and continuous learning programs, ensuring readiness, confidence, and sustained performance in role Contribute to building just-in-time learning approaches that support ongoing development and field application Support and operationalize the Field Trainer model, enabling Field Trainers to operate as an extension of the CT&D team through strong facilitation, coaching, and in-field execution Provide guidance, tools, and support to ensure consistent, high-quality delivery of learning initiatives Leverage data, insights, and field feedback to assess capability gaps, measure training effectiveness, and recommend improvements to learning strategies Track and report on key performance indicators (KPIs) to demonstrate the impact of training on behavior change and business outcomes Design, develop, and deploy learning materials and assets, ensuring alignment with brand strategy, clinical accuracy, and compliance requirements Manage the CRB submission process and ensure all training materials meet legal, regulatory, and medical standards Apply innovative learning approaches and technologies (e.g., simulations, AI-enabled tools, digital platforms) to enhance engagement, retention, and scalability Manage multiple learning initiatives and projects simultaneously, ensuring strong execution, clear communication, and alignment across stakeholders Collaborate with cross-functional teams to support National Sales Meetings (NSM), POA meetings, and other key field engagements, ensuring learning is impactful and aligned to business priorities Manage vendor relationships and project deliverables, ensuring high-quality, cost-effective execution of learning solutions Demonstrate a strong understanding of commercial strategy, sales operations, and field tools, ensuring training solutions are practical, relevant, and aligned to how the field operates Qualifications Bachelor’s degree required Must have a minimum of 5 years of experience in the Pharmaceutical Industry, Commercial field sales experience preferred Preferred to have a minimum of 2 years training experience in a headquarters role or as a field trainer Proven ability to translate business strategy into capability-building plans that drive measurable outcomes Demonstrated experience supporting product launches, complex therapeutic areas, or specialty markets preferred Strong understanding of clinical data and the ability to translate scientific concepts into clear, compelling learning experiences Demonstrated ability to influence cross-functional stakeholders and senior leaders in a highly matrixed environment Strong executive presence with the ability to facilitate both strategic discussions and engaging learning experiences Experience using data, insights, and performance metrics to identify capability gaps and measure training effectiveness and business impact Strong foundation in adult learning principles, instructional design, and modern learning approaches, including digital, virtual, and just-in-time learning Experience leveraging innovative learning solutions (e.g., simulations, AI-enabled tools, scalable learning platforms) preferred Excellent project management skills with the ability to manage multiple priorities, workstreams, and deadlines in a fast-paced environment Strong written and verbal communication skills, including presentation and facilitation excellence Ability to build trusted relationships and collaborate effectively across all levels of the organization Proficiency in Microsoft Office (PowerPoint, Excel, Word) and virtual learning platforms (e.g., Zoom or similar) Ability to travel up to 20% #LI-SS1 #LI-Remote U.S. Pay Range $147,100.00 - $198,900.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website https//www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. Apply To This Job